Lorenzo Lotto
The Madonna and Saints

Church of San Giacomo dall'Orio, Venice

The saints are James the Greater on the left (pilgrim's staff and garb) and Andrew on the right (cross saltire, long beard).

This image in full resolution

More of the Madonna Enthroned
More of St. James the Greater
More of St. Andrew

Photographed at the church by Richard Stracke, shared under Attribution-NonCommercial-ShareAlike license.